Frequency and Pattern of Congenital Heart Disease Among Neonates
DOI:
https://doi.org/10.59675/U411Keywords:
Congenital heart disease; Neonates; Echocardiography; ASD; VSD; PDA.Abstract
Background: Congenital heart disease (CHD) is among the most common congenital anomalies and a major contributor to neonatal morbidity and mortality worldwide. Local data from Iraq regarding the distribution of CHD among Iraqi neonates remain limited.
Objective: To determine the frequency and echocardiographic pattern of CHD among neonates referred for suspected congenital heart disease in Al-Diwaniyah, Iraq.
Methods: This hospital-based cross-sectional study was conducted from February to December 2024. A total of 934 neonates (0-28 days old) suspected of having CHD underwent echocardiographic examination. Diagnoses were classified into cyanotic and a cyanotic CHD. Data were analysed using SPSS. Frequencies and percentages were calculated. A Chi-square test was used to assess the association between sex and diagnosis. A p value <0.05 was considered statistically significant.
Results: Of 934 neonates, 600 (64.2%) were males and 334 (35.8%) were females. Congenital heart disease was diagnosed in 622 neonates (66.6%) while 312 neonates (33.4%) had normal echocardiographic findings. The most frequent lesions were Atrial septal defect (ASD), Ventricular septal defect (VSD), and patent ductus arteriosus (PDA). Cyanotic CHD including Tetralogy of Fallot (TOF) and transposition of great arteries (TGA) were less common. No statistically significant association was found between sex and type of diagnosis (p>0.05).
Conclusion: A Cyanotic lesion particularly ASD, VSD, and PDA were the most frequent echocardiographic diagnoses. Although male predominance was observed in referrals, the distribution of CHD types did not significantly differ between males and females. Early echocardiographic screening remains essential for timely detection and management.
References
1. Bernstein D. The fetal-to-neonatal circulatory transition. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, editors. Nelson Textbook of Pediatrics. 17th ed. Philadelphia: Saunders; 2004. p. 1479–1481.
2. van der Linde D, Konings EEM, Slager MA, Witsenburg M, Helbing WA, Takkenberg JJM, et al. Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis. J Am Coll Cardiol. 2011;58(21):2241–2247.
3. van der Bom T, Zomer AC, Zwinderman AH, Meijboom FJ, Bouma BJ, Mulder BJM. The changing epidemiology of congenital heart disease. Nat Rev Cardiol. 2011;8(1):50–60.
4. Khan A, Gurvitz M. Epidemiology of adult congenital heart disease: what has changed and what is changing? Prog Cardiovasc Dis. 2018;61(3-4):275–281.
5. Mandalenakis Z, Giang KW, Eriksson P, Liden H, Synnergren M, Wåhlander H, et al. Survival in children with congenital heart disease: have we reached a peak at 97%? J Am Heart Assoc. 2020;9(22):e017704.
6. Rahim F, Ebadi A, Saki G, Remazani A. Prevalence of congenital heart disease in Iran: a clinical study. J Med Sci. 2008; 8:547–552.
7. Pan F, Li J, Lou H, et al. Geographical and socioeconomic factors influence the birth prevalence of congenital heart disease: a population-based cross-sectional study in eastern China. Curr Probl Cardiol. 2022;47(11):101341.
8. Koyak Z, Harris L, de Groot JR, Silversides CK, Oechslin EN, Bouma BJ, et al. Sudden cardiac death in adult congenital heart disease. Circulation. 2012;126(16):1944–1954.
9. Nikyar B, Sedehi M, Mirfazeli A, Qorbani M, Golalipour MJ. Prevalence and pattern of congenital heart disease among neonates in Gorgan, Northern Iran (2007–2008). Iran J Pediatr. 2011;21(3):307–312.
10. Parvar SY, Ghaderpanah R, Naghshzan A. Prevalence of congenital heart disease according to echocardiography findings in 8145 neonates: multicenter study in southern Iran. Health Sci Rep. 2023;6(4): e1178.
11. Costello JM, Pasquali SK, Jacobs JP, He X, Hill KD, Cooper DS, et al. Gestational age at birth and outcomes after neonatal cardiac surgery: an analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database. Circulation. 2014;129(24):2511–2517.
12. Wilson E Sadoh 1, Ikechukwu Okonkwo 1, Fidelis E Eki-udoko 1, Promise Monday 1, Gold I Osueni 1, Jonathan Amake 1, Emmanuel Eyo-Ita 1, Chukwunwendu A Okonkwo 2, Ezinne Emeruwa 3, Barbara E Otaigbe 4, Gregrey A Oko-oboh etal. Birth prevalence of congenital heart disease among newborns in a tertiary hospital in Benin City, Nigeria Cardiovasc J Afr. 2021 Aug 5;32(5):267–270. doi: 10.5830/CVJA-2021-028
13. Flaminia Pugnaloni , Alessandro Felici , Antonio-Francesco Corno , Bruno Marino ,✉, Paolo Versacci , Carolina Putotto et al. Gender differences in congenital heart defects: a narrative review 2023 Sep 11;12(9):1753–1764. doi: 10.21037/tp-23-260
14. Mohaeman Mutalib Salih et al. Incidence of congenital heart diseases in the Neonatal Intensive Care unit in Al-Batool teaching hospital in Diyala Governorate – Iraq
15. Sayed Ali Amin, Sumer Nady Mohamed Elfakhrany , Ahmed Mahmoud Abd Elmoktader et al. Prevalence of congenital heart disease among neonates in Fayoum district Volume 78, September 2025, 101858
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Academic International Journal of Medical Update

This work is licensed under a Creative Commons Attribution 4.0 International License.


